Potential antimicrobial effects of pharmacognostic drugs

Novel Halogenated Pyrazine-Based Chalcones as Potential Antimicrobial Drugs.

Chalcones, i.e., compounds with the chemical pattern of 1,3-diphenylprop-2-en-1-ones, exert a wide range of bio-activities, e.g., antioxidant, anti-inflammatory, anticancer, anti-infective etc. Our research group has been focused on pyrazine analogues of chalcones; several series have been synthesized and tested in vitro on antifungal and antimycobacterial activity. The highest potency was exhi...

Antimicrobial Drugs

Antimicrobials are classified by the pathogens targeted, e.g. as antibacterials or antifungals. This grouping may be subdivided as antibacterials also include urinary antiseptics and anti-mycobacterial drugs. Antimicrobials, especially antibacterials, are strictly classified into chemotherapeutic agents (synthetic chemicals), and antibiotics, produced from living organisms, usually fungi. Howev...

The Potential Genotoxic Effects of Antineoplastic Drugs in Occupationally Exposed Nurses

Pharmacodynamics of antimicrobial drugs.

Knowledge of the antimicrobial pharmacodynamic characteristics of a drug (inhibition of growth, rate and extent of bactericidal action, and postantibiotic effect) provides a more rational basis for determination of optimal dosing regimens in terms of the dose and the dosing interval. This article reviews concepts of antimicrobial pharmacodynamics, the effect of pharmacodynamics on the emergence...

Pharmacognostic Study, Chemical Analysis and Antioxidant Potential of Leucas indica L. (R. Br.)

Background & Aim: Leucas indica L. (R. Br.) is a lesser known aromatic herb of family Lamiaceae. Traditionally it was use to cure cough and cold by tribals of Southern India. The present work was aimed to investigate its pharmacognostic characters, major phytochemicals and antioxidant potential as possible replacement of its allied members to reduce their exploitation....